Services

DOT handles all aspects of clinical trials from Phase I to Phase IV. Our monitors are highly educated and well experienced within various therapeutic areas. Our senior managers all have more than 10 years of clinical experience, including global trials. With our capable and knowledgeable monitors, we are always able to cultivate good relationships between the sites and our clients which makes our trials run smoothly and efficiently.

We always perform an optimum monitoring model for our clients with the guarantee of data quality and overall cost effectiveness.

  • Special Population Groups
  • Investigators-initiated Studies
  • Observational Studies
  • Medical device Studies

The following is a summary of our Therapeutic Experience:

Description Phase Subjects No. Population Route of Administration
Cardiovascular A trial to evaluate risk factors for occurrence of Acute Coronary Syndrome. Registry 9000 Patients with Cardiovascular disease -
Neurosurgery A trial to evaluate the stent treatment for Cerebral Artery Stenosis. 3 20 Patients with Cerebral Artery Stenosis Implantation
(Device)
Neurology A trial of a drug for Schizophrenia. 2a 10 Schizophrenia Patients Oral
A trial to evaluate the efficacy and safety of a drug in Muscular Dystrophies. 2 20 Duchenne Muscular Dystrophies Patients Injection
A trial to evaluate a drug for Mitochondrial encephalomyopathy, Lactic acidosis, and Stroke-like episodes (MELAS). 3 15 MELAS Patients Oral
Oncology A multi-center trial of a diagnostic drug for Bladder Cancer. 3 60 Patients with Bladder Cancer Oral
A global trial of a stent system for the treatment of Pancreatic Cancer. - 40 Patients with Resectable Pancreatic Cancer Implantation
(Device)
Urology A multi-center trial to evaluate the efficacy and safety of Overactive Bladder. 2 600 Patients with Overactive Bladder Transdermal
A double-blind evaluation trial of a drug for Overactive Bladder. 3 1000 Patients with Overactive Bladder Transdermal
A long-term safety evaluation trial of a drug for Overactive Bladder. 3 300 Patients with Overactive Bladder Transdermal
A multi-center trial to evaluate the efficacy and safety of Benign Prostatic Hyperplasia (BPH). 2 600 BPH Patients Oral
Gynecology A multi-center trial to evaluate a drug for Infertility. 3 100 Infertility Female Patients Injection
Orthopedics A global bridging trial of a drug for Hand Surgery. 3 100 Patients with Dupuytren's disease Injection
A trial to evaluate a prosthetic treatment for Rheumatism - 20 Rheumatoid Arthritis Patients Implantation
(Device)
Endocrine A global trial to evaluate the efficacy of a drug for Hyperlipidemia. 3 150 Patients with High Cholesterol Level Injection
Hematology A multi-center trial to evaluate the safety, pharmacokinetics and efficacy of a drug for Myelodysplastic Syndromes (MDS). 2 11 MDS Patients Oral
A multi-center trial to evaluate the efficacy of a drug for Thrombotic Thrombocytopenic Purpura (TTP) 2 6 TTP Patients Injection

JCROA CDISC

DOT WORLD Co., Ltd. Comodio Shiodome 4F, 2-14-1 Higashi-Shimbashi, Minato-ku, Tokyo, 105-0021, Japan